Table 1 Signalment and immunohistochemistry summary for all subjects evaluated

C-1

14

MC

Border Collie

n/a

(−)

n/a

Normal Lung

C-2

4

MC

Australian Shepherd

n/a

(−)

n/a

Normal Lung

C-3

7

MC

Mixed

n/a

(−)

n/a

Normal Lung

C-4

5

FS

Mixed

(+)

(−)

n/a

Normal Lung

C-5

8

MC

Dachshund

(+)

(−)

n/a

Normal Lung

C-6

8

MC

German Shepherd

n/a

(−)

n/a

Normal Lung

C-7

5

FS

Dachshund

n/a

(−)

n/a

Normal Lung

C-9

7

FS

Mixed

n/a

(−)

n/a

Normal Lung

C-10

7

MC

Doberman Pinscher

n/a

(−)

n/a

Normal Lung

C-15

13

MI

Mixed

(+)

(−)

n/a

Normal Lung

C-17

9

FS

Labrador Retriever

(+)

(−)

n/a

Normal Lung

C-18

7

FS

Shih Tzu

n/a

(−)

n/a

Normal Lung

C-19

9

MC

Boxer

n/a

(−)

n/a

Normal Lung

C-20

10

FI

Labrador Retriever

n/a

(−)

n/a

Normal Lung

C-21

12

MC

West Highland Terrier

(+)

(−)

n/a

Normal Lung

C-22

9

MC

Mixed

n/a

(−)

n/a

Normal Lung

O-2

10

MC

Weimaraner

(+)

(−)

(−)

Metastatic Osteosarcoma

O-3

8

MI

Rottweiler

(+)

(+)

(−)

Metastatic Osteosarcoma

O-4

7

MC

Golden Retriever

n/a

(+)

(+)

Metastatic Osteosarcoma

O-5

10

FS

Mixed

n/a

(−)

(+)

Metastatic Osteosarcoma

O-6

5

MC

Labrador Retriever

^a

^a

^a

Metastatic Osteosarcoma

O-9

10

FS

Staffordshire Terrier

(+)

(−)

(+)

Metastatic Osteosarcoma

O-10

8

MC

Great Dane

n/a

(−)

(+)

Metastatic Osteosarcoma

O-11

5

MC

Golden Retriever

(+)

(−)

(+)

Metastatic Osteosarcoma

O-12

10

FS

Mixed

(+)

(+)

(−)

Metastatic Osteosarcoma

O-13

11

FS

Mixed

(+)

(−)

(+)

Metastatic Osteosarcoma

P-1

11

MC

Mixed

(+)

(−)

(−)

Large cell carcinoma

P-3

14

FS

Bichon Frise

(+)

(+)

(+)

Bronchioloalveolar carcinoma

P-4

11

FS

Greyhound

(−)

(+)

(−)

Adenosquamous carcinoma

P-8

9

FS

Scottish Terrier

(+)

(−)

(−)

Bronchioloalveolar carcinoma

P-9

13

MC

Mixed

(+)

(+)

(−)

Bronchioloalveolar carcinoma

P-10

10

MC

Cocker Spaniel

(+)

(−)

(−)

Bronchioloalveolar carcinoma

P-12

10

FS

Boston Terrier

(+)

(−)

(+)

Bronchial gland carcinoma

P-13

10

MC

Boxer

^a

^a

^a

Acinar Pulmonary adenocarcinoma ^a

P-14

12

FS

Gordon Setter

(+)

(+)

(−)

Papillary adenocarcinoma

P-15

14

MC

Mixed

(+)

(−)

(+)

Papillary adenocarcinoma

P-16

14

FS

Welsh Corgi

(+)

(−)

(−)

Large cell carcinoma

P-17

15

MC

Welsh Corgi

(+)

(+)

(+)

Solid adenocarcinoma

P-19

11

FS

Mixed

(+)

(−)

(−)

Bronchioloalveolar carcinoma