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Table 1 Symptoms and Diagnostic Workup intra vitam

From: Post mortem computed tomography and core needle biopsy in comparison to autopsy in eleven bernese mountain dogs with histiocytic sarcoma

Dog

Sex

Age (y)

Medical history

Tests

Diagnostic results

HS

RS

1

F

9

Apathy, dyspnoea, collapse

B, R, U

Anaemia, hypoalbuminaemia; cranial intrathoracic mass; pleural effusion.

S

3

2

F

5.5

Apathy, anorexia, icterus

B, R

Anaemia, hypoproteinaemia, hyperbilirubinaemia; multinodular lung pattern, widened mediastinum.

S

3

3

F

8.5

Paraparesis

R

Pulmonary mass, widened mediastinum.

S

3

4

Fn

9

Apathy, anorexia, dyspnoea

R (m)

Growing pulmonary mass, widened mediastinum.

S

3

5

Mn

6

Weakness, anorexia, collapse, fever

B, U, C

Anaemia, thrombocytopenia, leucocytosis with neutrophilia; mass associated with the spleen, disseminated liver nodules, haemoabdomen.

S

3

6

M

7.5

Anorexia, vomiting

B, R

Anaemia, thrombocytopenia; pulmonary masses, tracheobronchial lymphadenomegaly.

S

3

7

M

6

Splenic mass

P, L, H

Splenic neoplasia, suspicion of HS.

S

3

8

F

7

Lameness

R

Aggressive bone lesions in left femur and tibia.

S

3

9

Fn

12

Weakness, lameness, dyspnoea

N

None.

N

2

10

Mn

3.5

Apathy, anorexia

B, R

Anaemia, thrombocytopenia; intrathoracic mass cranially; abdominal mass effect.

S

3

11

Fn

9

Lameness

R

Aggressive bone lesion in the right humerus.

S

3

  1. This table summarizes the details about the eleven Bernese mountain dogs, their medical history, the diagnostic methods used and their results. The last two columns show the diagnostic quality regarding HS and the reliability score of the diagnosis. For explanation, please consult the methods section of the text
  2. Abbreviations: y years, HS histiocytic sarcoma and the respective quality of diagnosis, S suspicion of histiocytic sarcoma, N none, RS reliability score [13] F female, M male, n neutred, B blood analysis, R radiography, m multiple consecutive radiographs, U ultrasonography, C cytology of abdominal fluid from peritoneocentesis, P abdominal palpation, L explorative laparotomy, H histology of splenic sample