Skip to main content

Table 3 Results for the immunoexpression of the ER-α and PR in the normal feline uterus (at the FS and LS) and in the neoplastic epithelium in FEA

From: An immunohistochemical study on the expression of sex steroid receptors, Ki-67 and cytokeratins 7 and 20 in feline endometrial adenocarcinomas

  Intensity Percentage of positive cells
n (%) n (%)
0 1 2 3 0 1 2
  ER-α
FS SE 0 0 7 (53.8) 6 (46.2) 0 0 13 (100.0)
SGE 0 0 3 (23.1) 10 (76.9) 0 0 13 (100.0)
DGE 0 0 1 (7.7) 12 (92.3) 0 0 13 (100.0)
Stroma 0 0 4 (30.8) 9 (69.2) 0 7 (53.8) 6 (46.2)
Myometrium 0 0 12 (92.3) 1 (7.7) 0 0 13 (100.0)
LS SE 0 3 (30.0) 5 (50.0) 2 (20.0) 0 2 (20.0) 8 (80.0)
SGE 0 0 6 (60.0) 4 (40.0) 0 0 10 (100.0)
DGE 0 0 0 10 (100.0) 0 0 10 (100.0)
Stroma 0 1 (10.0) 4 (40.0) 5 (50.0) 0 7 (70.0) 3 (30.0)
Myometrium 0 1 (10.0) 7 (70.0) 2 (20.0) 0 0 10 (100.0)
FEA Epithelium 12 (50.0) 5 (20.8) 6 (25.0) 1 (4.2) 12 (50.0) 11 (45.8) 1 (4.2)
Stroma 11 (45.8) 2 (8.3) 8 (33.3) 3 (12.5) 11 (45.8) 13 (54.2) 0
Myometrium 4 (16.7) 0 18 (75.0) 2 (8.3) 4 (16.7) 9 (37.5) 11 (45.8)
  PR
FS SE 0 1 (7.7) 7 (53.8) 5 (38.5) 0 0 13 (100.0)
SGE 0 1 (7.7) 7 (61.5) 5 (30.8) 0 0 13 (100.0)
DGE 0 2 (15.4) 5 (38.5) 6 (46.2) 0 0 13 (100.0)
Stroma 0 1 (7.7) 10 (76.9) 2 (15.4) 0 10 (76.9) 3 (23.1)
Myometrium 0 5 (38.5) 8 (61.5) 0 0 0 13 (100.0)
LS SE 0 0 5 (50.0) 5 (50.0) 0 1 (10.0) 9 (90.0)
SGE 0 0 5 (50.0) 5 (50.0) 0 1 (10.0) 9 (90.0)
DGE 0 1 (10.0) 3 (30.0) 6 (60.0) 0 1 (10.0) 9 (90.0)
Stroma 4 (40.0) 1 (10.0) 2 (20.0) 3 (30.0) 4 (40.0) 6 (60.0) 0
Myometrium 1 (10.0) 4 (40.0) 3 (30.0) 2 (20.0) 1 (10.0) 2 (20.0) 7 (70.0)
FEA Epithelium 0 1 (4.2) 19 (79.2) 4 (16.7) 0 7 (29.2) 17 (70.8)
Stroma 2 (8.3) 1 (4.2) 19 (79.2) 2 (8.3) 2 (8.3) 21 (87.5) 1 (4.2)
Myometrium 0 4 (16.7) 18 (75.0) 2 (8.3) 0 6 (25.0) 18 (75.0)
  1. SE = surface endometrium; SGE = superficial glandular epithelium; DGE = deep glandular epithelium; FS = follicular stage; LS = luteal stage.). Intensity of immunolabelling: 1 = weak, 2 = moderate and 3 = strong. Percentage of positive nuclei: 0 = negative (≤5 % positive nuclei); 1 = loss of expression (5-80 % positive nuclei) and 2 = positive (≥80 % positive nuclei)