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Table 4 The experimental design in the study

From: Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia

Groups

Number of rats

Food

Drug

Dosage

Average volume per rat

A

10

Basal diet

--

--

--

B

10

HFD diet

--

--

--

C

10

HFD diet

AEE

18 mg/kg

0.58 ml

D

10

HFD diet

AEE

36 mg/kg

1.17 ml

E

10

HFD diet

AEE

54 mg/kg

1.72 ml

F

10

HFD diet

ASA+ Eugenol

(20 + 18) mg/kg

1.19 ml

G

10

HFD diet

ASA

20 mg/kg

0.65 ml

H

10

HFD diet

Eugenol

18 mg/kg

0.54 ml

I

10

HFD diet

Simvastatin

10 mg/kg

0.63 ml

J

10

HFD diet

CMC-Na

20 mg/kg

1.28 ml

  1. Note: HFD: high fat diet. A: blank group, B: model group, C:EE low dose, D: AEE medium dose, E: AEE high dose, F: integration group (ASA: eugenol, molar ratio 1:1), G: acetylsalicylic acid (ASA) group, H: eugenol group, I: simvastatin group, J: CMC-Na group. At the end of 4th, 6th, 8th, 10th and 13th week after HFD was used, the rats were fasted for 10–12 h and anesthetized with 10 % chloral hydrate. Approximately 1.5 ml blood samples were taken from tail tip for blood lipids examination