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Table 1 Concentrations of LBP, Lf, Hp, and CRP in the blood sera of calves

From: Acute phase proteins as local biomarkers of respiratory infection in calves

APP Healthy animals Number Infection with Chlamydia psittaci (2–3 dpi) Number Infection with Parachlamydia acanthamoebae (1 dpi) Number Studies calves were enrolled in
LBP [μg × mL−1] 6.0 (1.0–69.8) 123 136.6*** (25.9–470.0) 80a 15.0*** (3.1–75.6) 21c [27, 31, 34]
Lf [ng × mL−1] 146.3 (71.4–345.8) 43 NA   190.1** (72.0–393.5) 21c [27]
Hp [μg × mL−1] 5.8 (0.03–127.6) 69 29.9*** (0.9–3048.8) 35b NA   [30, 28, 29, 33]
CRP [μg × mL−1] 47.8 (8.3–178.7) 69 56.1 (13.6–147.7) 35b NA   [30, 28, 29, 33]
  1. LBP lipopolysaccharide binding protein; Lf lactoferrin; Hp haptoglobin; CRP C-reactive protein. Values are given as median (minimum-maximum). Age, origin and breed of the calves and methods of marker detection were identical with this study. Data related to infected animals are given at that time point (day post inoculation (dpi)), where they were maximal within an observation period of 2 weeks after inoculation. For statistical evaluation, values from the day with the highest values were compared to pre-inoculation values of the same animals (Mann–Whitney-U test). **0.001 ≤ P < 0.01; *** P < 0.0001. aanimals inoculated with 108 inclusion forming units (ifu); banimals inoculated with 106, 107, 108, or 109 ifu; canimals inoculated with 1010 ifu. NA not analyzed