Table 6 Brain lesion types
Pathological lesion category | Type & underlying pathology | |
|---|---|---|
PL-1: Discolouration | Pallor | a. oedema |
b. gliosis, sclerosis, fibrosis | ||
c. coagulation necrosis | ||
d. mineralisation | ||
e. infiltrative disease | ||
Greyish | a. oedema | |
b. colliquative necrosis | ||
c. infiltrative disease | ||
Yellow | a. pus | |
b. caseous necrosis | ||
c. nuclear jaundice | ||
Brown | a. lipofuscinergic | |
b. siderosis | ||
Black | a. melanin | |
b. blood | ||
Red | blood | |
Pink | carbon monoxide | |
PL-2: Loss & gain of tissue | Architecture sparing: disproportion & asymmetry | |
1. Gain | a. regional oedema/inflammation | |
b. malformation (e.g. macrogyria) | ||
c. harmatoma | ||
d. low grade glioma | ||
2. Loss | a. atrophy/neurodegeneration | |
b. hypoplasia | ||
With architectural changes | ||
1. Gain | a. oedema | |
b. infiltrative disease | ||
2. Loss | a. atrophy | |
b. degeneration/necrosis | ||
3. Topographical | a. misplacement (e.g. heterotopia) | |
b. disorganisation (dysplasia) | ||
PL-3: Textural change | Induration | a. glial/sclerosis |
b. neoplasia | ||
c. fibrosis | ||
d. mineralisation | ||
Softening | a. oedema | |
b. collequative necrosis | ||
c. inflammation | ||
d. neoplasia | ||