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Table 1 Quantitative histological results

From: Effects of diacerein on cartilage and subchondral bone in early stages of osteoarthritis in a rabbit model

 

CTRL

OA

CTRL + DC

OA + DC

 

mean ± std.dev

mean ± std.dev

mean ± std.dev

mean ± std.dev

Subchondral bone

Tb.A (mm2)

46.37 ± 5.41

47.93 ± 7.01

50.69 ± 7.34

45.54 ± 6.83

Tb.Sp (μm)

514.93 ± 235.24

437.79 ± 211.86

534.56 ± 222.56

590.16 ± 272.66

SB.Th (μm)

306.57 ± 76.46

251.60 ± 67.43

264.07 ± 28.36

268.20 ± 47.01

Cartilage

FI (mm)

1.08 ± 0.07

1.22 ± 0.14

1.10 ± 0.16

1.10 ± 0.05

Cg.Th (μm)

493.73 ± 80.73

620.12 ± 114.82c

473.82 ± 87.57b

571.12 ± 96.73

nCg.Th (μm)

338.64 ± 65.03b

465.23 ± 88.92a,c

322.19 ± 82.98b

409.79 ± 82.56

cCg.Th (μm)

155.09 ± 24.94

167.75 ± 43.01

151.69 ± 28.05

161.33 ± 42.09

  1. Comparison of the histological parameters obtained from undecalcified samples between experimental groups. All variables were normally distributed, except FI. Statistical significance p < 0.05: a vs. CTRL; b vs. OA; c vs. CTRL + DC; d vs. OA + DC