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Table 2 Adverse events in toceranib treated dogs

From: Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma

Adverse event Grade
  1 2 3 4 5
Vomiting 38 2 2   
Diarrhea 32 9 2   
Decreased HCT (Anemia) 26 13 2 2  
Inappetance 20 6 3   
Decreased hemoglobin 17 5 2 1  
Weight Loss 11 1    
Neutropenia 8 3    
Increased CK 8     
Lethargy 6 7   2  
Elevated BUN 6 2 1 1  
Alopecia 5 1    
Hind limb weakness 4 3 2   
Hypoalbuminemia 3     
Nausea 3     
Lameness 1     
Trembling hind limbs 1     
GI blood loss 1 2    
Stiffness   3    
Pancreatitis   2    
Generalized weakness   1   3  
Hemoabdomen   1   6 3