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Table 2 Adverse events in toceranib treated dogs

From: Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma

Adverse event

Grade

 

1

2

3

4

5

Vomiting

38

2

2

  

Diarrhea

32

9

2

  

Decreased HCT (Anemia)

26

13

2

2

 

Inappetance

20

6

3

  

Decreased hemoglobin

17

5

2

1

 

Weight Loss

11

1

   

Neutropenia

8

3

   

Increased CK

8

    

Lethargy

6

7

 

2

 

Elevated BUN

6

2

1

1

 

Alopecia

5

1

   

Hind limb weakness

4

3

2

  

Hypoalbuminemia

3

    

Nausea

3

    

Lameness

1

    

Trembling hind limbs

1

    

GI blood loss

1

2

   

Stiffness

 

3

   

Pancreatitis

 

2

   

Generalized weakness

 

1

 

3

 

Hemoabdomen

 

1

 

6

3