Parameters | Goat | Sheep | ||
---|---|---|---|---|
ABZ-SO | ABZ-SO2 | ABZ-SO | ABZ-SO2 | |
T1/2λz (h) | 5.43 ± 0.89* | 3.53 ± 0.81* | 6.57 ± 0.73 | 11.43 ± 9.41 |
Cmax (μg/mL) | - | 0.62 ± 0.21 | - | 0.46 ± 0.05 |
C0 (μg/mL) | 10.84 ± 1.81 | - | 10.86 ± 1.82 | - |
Tmax (h) | - | 15.00 ± 6.48* | - | 8.50 ± 3.34 |
Tlast (h) | 21.00 ± 4.14* | 25.00 ± 10.56 | 30.00 ± 3.70 | 31.00 ± 2.83 |
AUClast (μg.h/mL) | 34.10 ± 5.31* | 10.49 ± 4.26 | 39.15 ± 5.59 | 11.00 ± 0.78 |
AUCMlast (μg.h2/mL) | 201.91 ± 58.84* | 133.34 ± 65.25 | 293.46 ± 64.66 | 155.96 ± 17.30 |
Cl (L/h/kg) | 0.14 ± 0.03 | - | 0.13 ± 0.02 | - |
MRTlast (h) | 5.81 ± 0.86* | 12.31 ± 4.95 | 7.44 ± 1.03 | 14.18 ± 1.28 |
Vdss (L/kg) | 0.94 ± 0.09 | - | 1.04 ± 0.14 | - |