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Table 1 Risk of bias of selected clinical studies

From: Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions

 

Random sequence generation (selection bias)

Allocation concealment (selection bias)

Blinding of participants and personnel (performance bias)

Blinding of outcome assessment (detection bias) (patient-reported outcomes)

Blinding of outcome assessment (detection bias) (all-cause mortality)

Incomplete outcome data (attrition bias) (short-term [2-6 weeks])

Incomplete outcome data (attrition bias) (long-term[> 6 weeks])

Selective repoorting (reporting bias)

Risk of bias

Garret 2013

+

+

-

+

-

+

+

-

↓

Zuffova 2013

-

-

-

-

-

+

+

+

↑

Edinger 2012

-

-

-

-

-

-

-

-

↑

Torricelli 2011

-

-

-

-

-

+

+

+

↑

Castelijns 2011

-

-

-

-

-

+

+

+

↑

Georg 2010

-

-

-

-

-

+

?

-

↑

Abelanet 2009

-

-

-

-

-

+

+

-

↑

Carmona 2009

-

-

-

-

-

+

+

+

↑

Waselau 2008

-

-

-

-

-

+

+

+

↑

Arguelles 2008

-

-

-

-

-

+

+

+

↑

Carmona 2007

-

-

-

-

-

+

+

+

↑

Tiwari 2013

?

-

-

-

?

+

+

-

↑

Antuna 2013

+

+

-

+

+

+

+

+

↓

Magnussen 2013

-

-

-

-

-

+

+

+

↑

Mishra 2014

+

+

-

+

+

+

+

+

↓

Krogh 2013

+

+

-

+

+

+

+

+

↓

Patel 2013

+

?

?

?

?

+

+

-

↑

Wasterlain 2012

+

+

-

+

+

+

+

+

↓

Jain 2012

+

+

+

+

+

+

+

+

↓

Mardones 2012

+

+

+

+

+

+

+

+

↓

Cerza 2012

-

-

-

-

-

+

+

+

↑

Mei-Dan 2012

+

-

-

-

+

+

+

+

↑

Almeida 2012

+

-

-

-

+

+

+

+

↓

Spaková 2012

-

-

-

-

-

+

+

+

↑

Aksahin 2012

-

-

-

+

-

+

+

+

?

Rodeo 2012

+

+

+

+

+

+

+

+

↓

Weber 2012

+

-

+

+

+

+

+

+

↓

Bergeson 2012

-

-

-

-

+

+

+

+

?

Cervelin 2012

+

+

?

-

+

+

+

-

↓

Filardo 2012

+

+

+

+

+

+

-

+

↓

Jo 2011

-

-

-

-

-

+

+

+

↑

Randelli 2011

+

+

+

+

+

+

+

+

↓

Castricini 2011

+

+

+

+

+

+

+

+

↓

Thanasas 2011

+

+

-

+

+

+

+

+

↓

Schepul 2011

+

+

+

+

+

+

+

+

↓

De Vos 2011

+

+

+

+

+

+

+

+

↓

Creaney 2011

+

+

+

+

+

+

+

+

↓

Kon 2011

-

-

-

-

-

+

+

+

↑

Jonge 2011

+

+

+

+

+

+

-

+

↓

Gosens 2011

?

?

+

+

+

+

+

+

↓

Barber 2011

-

-

-

-

-

+

+

+

↑

Horstman 2011

+

+

+

+

+

+

+

+

↓

Buford 2011

-

-

-

-

-

+

+

+

↑

Vogrin 2010

+

+

+

+

+

+

+

+

↓

Peerboms 2010

+

+

+

+

+

+

+

+

↓

De Vos 2010

+

+

+

+

+

+

+

+

↓

Radice 2010

-

-

-

-

+

+

+

+

?

Filardo 2010

-

-

-

-

-

+

+

-

↑

Nin 2009

+

+

+

+

+

+

+

+

↓

Silva 2009

-

-

-

-

-

+

+

+

↑

Peerboms 2009

?

+

+

+

+

+

-

+

↓

Sanchez 2008

-

-

-

-

-

-

?

+

↑

Everts 2008

+

+

+

+

+

+

+

+

↓

Orrego 2008

+

+

-

+

+

+

+

+

↓

Sanchez 2007

-

-

-

-

-

+

+

+

↑

Everts 2007

-

-

-

-

-

+

+

+

↑

Gardner 2007

-

-

-

-

-

+

+

+

↑

Zavadil 2007

+

+

+

+

+

+

+

+

↓

Mishra 2006

-

-

-

-

-

+

-

+

↑

Ventura 2005

+

+

-

-

-

+

+

+

↓