| Random sequence generation (selection bias) | Allocation concealment (selection bias) | Blinding of participants and personnel (performance bias) | Blinding of outcome assessment (detection bias) (patient-reported outcomes) | Blinding of outcome assessment (detection bias) (all-cause mortality) | Incomplete outcome data (attrition bias) (short-term [2-6 weeks]) | Incomplete outcome data (attrition bias) (long-term[> 6 weeks]) | Selective repoorting (reporting bias) | Risk of bias |
---|---|---|---|---|---|---|---|---|---|
Garret 2013 | + | + | - | + | - | + | + | - | ↓ |
Zuffova 2013 | - | - | - | - | - | + | + | + | ↑ |
Edinger 2012 | - | - | - | - | - | - | - | - | ↑ |
Torricelli 2011 | - | - | - | - | - | + | + | + | ↑ |
Castelijns 2011 | - | - | - | - | - | + | + | + | ↑ |
Georg 2010 | - | - | - | - | - | + | ? | - | ↑ |
Abelanet 2009 | - | - | - | - | - | + | + | - | ↑ |
Carmona 2009 | - | - | - | - | - | + | + | + | ↑ |
Waselau 2008 | - | - | - | - | - | + | + | + | ↑ |
Arguelles 2008 | - | - | - | - | - | + | + | + | ↑ |
Carmona 2007 | - | - | - | - | - | + | + | + | ↑ |
Tiwari 2013 | ? | - | - | - | ? | + | + | - | ↑ |
Antuna 2013 | + | + | - | + | + | + | + | + | ↓ |
Magnussen 2013 | - | - | - | - | - | + | + | + | ↑ |
Mishra 2014 | + | + | - | + | + | + | + | + | ↓ |
Krogh 2013 | + | + | - | + | + | + | + | + | ↓ |
Patel 2013 | + | ? | ? | ? | ? | + | + | - | ↑ |
Wasterlain 2012 | + | + | - | + | + | + | + | + | ↓ |
Jain 2012 | + | + | + | + | + | + | + | + | ↓ |
Mardones 2012 | + | + | + | + | + | + | + | + | ↓ |
Cerza 2012 | - | - | - | - | - | + | + | + | ↑ |
Mei-Dan 2012 | + | - | - | - | + | + | + | + | ↑ |
Almeida 2012 | + | - | - | - | + | + | + | + | ↓ |
Spaková 2012 | - | - | - | - | - | + | + | + | ↑ |
Aksahin 2012 | - | - | - | + | - | + | + | + | ? |
Rodeo 2012 | + | + | + | + | + | + | + | + | ↓ |
Weber 2012 | + | - | + | + | + | + | + | + | ↓ |
Bergeson 2012 | - | - | - | - | + | + | + | + | ? |
Cervelin 2012 | + | + | ? | - | + | + | + | - | ↓ |
Filardo 2012 | + | + | + | + | + | + | - | + | ↓ |
Jo 2011 | - | - | - | - | - | + | + | + | ↑ |
Randelli 2011 | + | + | + | + | + | + | + | + | ↓ |
Castricini 2011 | + | + | + | + | + | + | + | + | ↓ |
Thanasas 2011 | + | + | - | + | + | + | + | + | ↓ |
Schepul 2011 | + | + | + | + | + | + | + | + | ↓ |
De Vos 2011 | + | + | + | + | + | + | + | + | ↓ |
Creaney 2011 | + | + | + | + | + | + | + | + | ↓ |
Kon 2011 | - | - | - | - | - | + | + | + | ↑ |
Jonge 2011 | + | + | + | + | + | + | - | + | ↓ |
Gosens 2011 | ? | ? | + | + | + | + | + | + | ↓ |
Barber 2011 | - | - | - | - | - | + | + | + | ↑ |
Horstman 2011 | + | + | + | + | + | + | + | + | ↓ |
Buford 2011 | - | - | - | - | - | + | + | + | ↑ |
Vogrin 2010 | + | + | + | + | + | + | + | + | ↓ |
Peerboms 2010 | + | + | + | + | + | + | + | + | ↓ |
De Vos 2010 | + | + | + | + | + | + | + | + | ↓ |
Radice 2010 | - | - | - | - | + | + | + | + | ? |
Filardo 2010 | - | - | - | - | - | + | + | - | ↑ |
Nin 2009 | + | + | + | + | + | + | + | + | ↓ |
Silva 2009 | - | - | - | - | - | + | + | + | ↑ |
Peerboms 2009 | ? | + | + | + | + | + | - | + | ↓ |
Sanchez 2008 | - | - | - | - | - | - | ? | + | ↑ |
Everts 2008 | + | + | + | + | + | + | + | + | ↓ |
Orrego 2008 | + | + | - | + | + | + | + | + | ↓ |
Sanchez 2007 | - | - | - | - | - | + | + | + | ↑ |
Everts 2007 | - | - | - | - | - | + | + | + | ↑ |
Gardner 2007 | - | - | - | - | - | + | + | + | ↑ |
Zavadil 2007 | + | + | + | + | + | + | + | + | ↓ |
Mishra 2006 | - | - | - | - | - | + | - | + | ↑ |
Ventura 2005 | + | + | - | - | - | + | + | + | ↓ |