Figure 9From: Alexander disease in a dog: case presentation of electrodiagnostic, magnetic resonance imaging and histopathologic findings with review of literatureWhite matter in brainstem. High power magnification shows intensely eosinophilic fibrinoid like droplets in the perivascular Rosenthal fibers. There is also marked accumulation of many abnormal astrocytes (arrows) with large smooth cytoplasm. HE 400 X.Back to article page