Table 5 Baseline, surgery and anaesthetic variables
Variable | Robenacoxib (s.c. + oral) | Meloxicam s.c. + placebo oral | Total | P value |
|---|---|---|---|---|
Total | 101 | 46 | 147 | |
Age | 3.8 (4.1) | 2.9 (3.1) | 3.5 (3.8) | 0.075 |
Body weight | 4.0 (1.0) | 3.8 (1.0) | 3.9 (1.0) | 0.26 |
Sex and neutered status | ||||
Male not neutered | 22 (22%) | 16 (35%) | 38 (26%) | 0.19 |
Female not neutered | 12 (12%) | 8 (17%) | 20 (14%) | |
Male neutered | 38 (38%) | 15 (33%) | 53 (36%) | |
Female neutered | 29 (29%) | 7 (15%) | 36 (24%) | |
Breed | ||||
Burmese | 1 (1%) | 0 (0%) | 1 (1%) | 0.37 |
Crossbred | 3 (3%) | 0 (0%) | 3 (2%) | |
Domestic long hair | 5 (5%) | 0 (0%) | 5 (3%) | |
Domestic short hair | 33 (33%) | 15 (33%) | 48 (33%) | |
European | 57 (56%) | 29 (63%) | 86 (59%) | |
Persian | 1 (1%) | 0 (0%) | 1 (1%) | |
Siamese | 1 (1%) | 2 (4%) | 3 (2%) | |
Baseline clinician scores | ||||
Global investigator score | 3.1 (1.9) | 3.5 (2.3) | 3.2 (2.0) | 0.50 |
Pain at palpation/manipulation | 1.5 (0.8) | 1.6 (0.8) | 1.5 (0.8) | 0.44 |
Expected duration of surgery (hours) | ||||
<60 min | 71 (70%) | 30 (65%) | 101 (69%) | 0.57 |
>60 min | 30 (30%) | 16 (35%) | 46 (31%) | |
Effective duration of surgery (hours) | 53.0 (38.8) | 57.9 (39.2) | 54.6 (38.8) | 0.41 |
Effective duration of intubation | 80.4 (48.5) | 79.5 (50.0) | 80.2 (48.8) | 0.82 |
Type of surgery | ||||
Fracture, internal repair | 49 (49%) | 26 (57%) | 75 (51%) | 0.38 |
Fracture, no internal repair | 1 (1%) | 0 (0%) | 1 (1%) | 1.0 |
Hip surgery | 10 (10%) | 4 (9%) | 14 (10%) | 1.0 |
Amputation, limb | 6 (6%) | 0 (0%) | 6 (4%) | 0.18 |
Amputation, tail or phalanx | 6 (6%) | 4 (9%) | 10 (7%) | 0.73 |
Joint surgery | 13 (13%) | 6 (13%) | 19 (13%) | 1.0 |
Removal of osteosynthesis material | 13 (13%) | 3 (7%) | 16 (11%) | 0.28 |
Miscellaneous | 2 (2%) | 2 (4%) | 4 (3%) | 0.59 |
Combinations | 1 (1%) | 1 (2%) | 2 (1%) | 1.0 |
Substances used in anaesthesia | ||||
Acepromazine | 22 (22%) | 12 (26%) | 34 (23%) | 0.67 |
Butorphanol | 33 (33%) | 15 (33%) | 48 (33%) | 1.0 |
Diazepam | 6 (6%) | 4 (9%) | 10 (7%) | 0.73 |
Ketamine | 57 (56%) | 28 (61%) | 85 (58%) | 0.72 |
Medetomidine | 54 (53%) | 17 (37%) | 71 (48%) | 0.076 |
Medetomidine/acepromazine | 0 (0%) | 1 (2%) | 1 (1%) | 0.31 |
Propofol | 33 (33%) | 12 (26%) | 45 (31%) | 0.450 |
Thiopental | 5 (5%) | 3 (7%) | 8 (5%) | 1.0 |
Tiletamine/zolazepam | 7 (7%) | 2 (4%) | 9 (6%) | 0.72 |
Xylazine | 18 (18%) | 11 (24%) | 29 (20%) | 0.50 |