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Table 2 Dosing and monitoring schedule

From: Robenacoxib versus meloxicam for the control of peri-operative pain and inflammation associated with orthopaedic surgery in cats: a randomised clinical trial

 

Day 0

Day 1

Day 2 to 9

Day 10

Time (T)

Initial visit

T0*

T1a

T1 + 3 hours (±0.5 hours)

T1 + 8 hours (±1 hours)

T1 + 22 hours (±2 hours)

T2b

T2 + 4 hours (±2 hours)

 

Final visit (±2 days)

Description

V1

  

V2

V3

V4

 

V5

 

VF

Location

Clinic

Clinic

Clinic

Clinic

Clinic

Clinic

Clinic

Clinic

Home

Clinic

Activity

 

Administer s.c. injection Anaesthesia induction

Extubation

   

First oral dose

 

Once-daily oral dosesc

 
  1. s.c.: subcutaneous; V: visit; VF: final visit.
  2. *The s.c. first drug administration was close to the time of anaesthetic induction (T0).
  3. aTime of extubation if the cat was intubated during anaesthesia or return of palpebral reflex if not intubated (T1).
  4. bThe first tablet was administered by the dispenser approximately 24 hours after the s.c. administration (T2).
  5. cTablets were administered from Day 2 to the day preceding the VF by the owner. The total duration of oral dosing was 9 days (range, 7–11 days).