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Table 3 Cultural isolation of MAP and lesions in extra-intestinal sites

From: Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection

Group Animal No. Liver Hepatic LN Spleen Retropharyngeal LN Tonsil
Culture gInf MAP-IHC Culture gInf MAP-IHC Culture gInf MAP-IHC Culture gInf MAP-IHC Culture gInf MAP-IHC
V1 7 0a) 0 0 0 0 0 0 0 0 0 0 0 0 0 0
8 33.33 +++b) 0 25.00 ++ 0 12.50 0 0 10.42 0 0 26.04 ++ 0
9 0 0 0 13.93 0 0 0 0 0 0 0 0 0 0 0
10 21.78 ++ 0 14.16 0 0 11.46 0 0 0 0 0 0 0 0
11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
12 0 + 0 0 0 0 0 0 0 0 0 0 0 0 0
13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
V2 14c) co. 0 0 0 ++ 0 0 0 0 0 0 0 0 0 0
15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
16c) 0 0 0 1.9 + 0 0 0 0 0 0 0 0 0 0
17c) 0 0 0 0 ++ 0 0 0 0 5.26 0 0 0 0 0
18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
19 0 +++ 0 6.6 ++ 0 0 0 0 4.16 + 0 3.57 0 0
20c) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
V3 27 12.50 0 0 8.33 0 0 0 0 0 0 0 0 0 0 0
28 co. 0 0 0 0 0 0 0 0 0 0 0 0 0 0
29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
V4 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
35 16.78 0 0 8.33 0 0 0 0 0 8.33 0 0 0 0 0
36d) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
37 4.29 0 0 22.50 0 0 0 0 0 7.94 0 0 0 0 0
38 co. 0 0 0 0 0 0 0 0 0 0 0 0 0 0
39 co. 0 0 0 0 0 0 0 0 0 0 0 0 0 0
  1. a)Growth Index b)granulomatous infiltrate: 0, none; +, mild, focal; ++, moderate, multifocal; +++, severe, diffuse; c)necropsy at 37–39 wpi; d)necropsy at 35 wpi; co. contaminated; na. not available; gInf, granulomatous infiltrate; MAP IHC, MAP antigen detected by IHC.
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BMC Veterinary Research

ISSN: 1746-6148

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