Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection

Köhler, Heike; Soschinka, Anneka; Meyer, Michaela; Kather, Angela; Reinhold, Petra; Liebler-Tenorio, Elisabeth

doi:10.1186/s12917-015-0381-1

Table 2 Cultural detection of MAP in intestinal mucosa, oGALT and intestinal lymph nodes of the MAP-inoculated goats at necropsy

From: Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection

Group	Animal No.	Jejunal LNN			Ileocol	LNN		JPP	IPP		ICVPP	PCPP	oGALT		Duoden	Jejunum			Intestine		Summary BOB cat.
Group	Animal No.	prox.	median	distal	LN	BOB	BOB cat.		prox.	distal			BOB	BOB cat.		1	2	3	BOB	BOB cat.	Summary BOB cat.
V1	7	0^a)	0	0	0	0	I ^b)	0	0	0	0	0	0	I	0	0	0	0	0	I	I
	8^c)	3.85	25.00	25.00	37.50	22.84	III	25.00	0	20.14	21.53	21.53	17.64	III	25.00	8.42	8.33	20.14	15.47	III	III
	9	22.63	50.00	40.00	40.00	38.16	III	40.00	35.00	40.00	62.50	co.	44.38	III	co.	23.57	40.00	40.00	34.52	III	III
	10	15.00	32.50	25.00	40.00	28.13	III	38.75	33.33	26.25	co.	co.	32.78	III	7.50	40.00	38.75	37.50	30.94	III	III
	11	0	4.96	6.75	6.25	4.49	II	0	0	0	3.13	0	0.63	II	co.	0	16.52	0	5.51	II	II
	12	0	0	0	0	0	I	0	0	0	co.	0	0	I	0	0	0	0	0	I	I
	13	17.80	11.11	0	22.22	12.78	II	0	0	0	22.22	5.56	5.55	II	0	16.67	16.67	25.00	14.58	II	II
V2	14^d)	0	0	7.29	0	1.82	II	0	0	co.	8.33	0	2.08	II	0	0	co.	co.	0	I	II
	15	16.67	8.33	8.33	8.33	10.42	II	16.67	0	4.17	0	8.33	5.83	II	0	8.33	0	0	2.08	II	II
	16^e)	12.46	8.33	10.06	0	7.71	II	14.38	16.67	12.79	12.11	0	11.19	II	0	12.84	0	5.55	4.60	II	II
	17^f)	0	0	0	7.50	1.88	II	n.a.	0	0	0	1.85	0.46	II	0	0	0	0	0	I	II
	18	0	0	0	0	0	I	0	0	0	0	0	0	I	0	0	0	0	0	I	I
	19	6.25	20.83	25.00	31.89	20.97	III	20.83	11.11	26.39	16.67	co.	18.75	III	0	16.67	20.83	20.83	14.58	II	III
	20^g)	0	0	0	0	0	I	0	0	0	0	0	0	I	0	16.67	0	0	0.42	II	II
V3	27	17.14	12.33	15.48	36.61	20.39	III	4.17	9.72	15.47	16.67	8.33	10.87	II	0	15.08	32.14	20.24	16.87	III	III
	28	13.26	14.44	4.17	9.33	10.30	II	8.33	2.17	0	9.33	co.	4.96	II	5.00	8.33	11.11	10.00	8.61	II	II
	29	0	4.80	5.88	0	2.67	II	co.	0	0	5.00	co.	1.67	II	0	0	0	0	0	I	II
	30	0	3.75	0	8.69	3.11	II	16.67	0	2.50	10.00	33.33	12.50	II	0	10.00	0	0	2.50	II	II
	31	0	0	0	8.63	2.16	II	co.	0	0	0	0	0	I	co.	0	0	0	0	I	II
	32	0	0	0	2.00	0.5	II	0	0	0	0	co.	0	I	0	0	0	0	0	I	II
V4	33	10.24	12.54	9.42	20.51	13.18	II	4.76	0	0	0	18.89	4.73	II	0	8.33	25.00	0	8.33	II	II
	34	9.40	16.91	0	11.11	9.35	II	co.	0	0	0	0	0	I	0	0	19.09	8.33	6.86	II	II
	35	33.33	33.33	1.85	41.67	27.55	III	37.37	0	25.00	16.67	20.21	19.85	III	4.17	16.67	25.00	16.67	15.62	III	III
	36^h)	8.89	13.29	16.67	0	9.71	II	0	10.00	8.33	14.34	13.33	9.20	II	3.33	0	co.	0	1.11	II	II
	37	35.00	30.00	35.00	40.00	35.00	III	33.33	23.81	8.33	co.	4.76	17.56	III	0	33.33	35.71	10.00	19.76	III	III
	38	6.67	0	18.75	15.86	10.31	II	co.	co.	co.	0	0	0	I	0	co.	co.	0	0	I	II
	39	0	0	0	0	0	I	0	0	0	0	0	0	I	0	0	0	0	0	I	I

^a)Growth Index ^b)BOB category: I, no growth; II, BOB ≤ 15; III, BOB > 15; ^c)cachectic; ^d)died 39 wpi; ^e)necropsied 37 wpi, diarrhea; ^f)died 37 wpi; ^g)necropsied 38 wpi; ^h)necropsied 35 wpi, diarrhea; prox. proximal; Ileocol Ileocolic; Duoden Duodenum; co. contaminated; n.a. not available.

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