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Table 6 The cell number of IgM + cells, KUL01 + macrophages, CD3 + CD4 + cells and CD3 + CD8 + cells in bursae and spleens of 3-week-old chickens infected with vvIBDV strain UPM0081 at 2, 4 and 5 dpi

From: Differential modulation of immune response and cytokine profiles in the bursae and spleen of chickens infected with very virulent infectious bursal disease virus

   Bursae (x10 6 cell/bursae) Spleen (x10 6 cell/spleen)
Average number of cells Day 0 230.00 ± 2.73a 190.00 ± 3.41a
  Day 2 173.00 ± 3.64b 150.00 ± 2.76b
  Day 4 116.00 ± 1.66c 66.40 ± 2.31c
  Day 5 54.00 ± 1.37d 34.40 ± 2.32d
IgM+ Day 0 189.83 ± 0.83a 57.36 ± 1.21a
  Day 2 138.99 ± 0.50b 44.35 ± 0.15b
  Day 4 72.21 ± 0.55c 23.27 ± 1.00c
  Day 5 35.52 ± 3.07d 14.57 ± 1.55d
KUL-1+ Day 0 9.90 ± 0.52a 6.26 ± 0.13a
  Day 2 8.76 ± 0.22a 18.54 ± 0.93b
  Day 4 20.68 ± 2.16b 2.08 ± 0.31c
  Day 5 12.92 ± 3.50c 2.75 ± 0.49c
CD3+CD4+ Day 0 1.73 ± 0.12a 41.49 ± 0.80a
  Day 2 1.67 ± 0.09a 33.04 ± 1.51b
  Day 4 3.82 ± 0.43b 16.52 ± 2.12c
  Day 5 4.25 ± 0.48b 7.58 ± 0.53d
CD3+CD8+ Day 0 1.67 ± 0.14a 62.36 ± 0.61a
  Day 2 1.86 ± 0.30a 48.68 ± 0.98b
  Day 4 3.05 ± 0.38b 20.87 ± 0.66c
  Day 5 3.52 ± 0.20b 6.81 ± 0.38d
  1. The number of cell (mean ± SD) of the cell subsets were determined by trypan blue cell count and flow cytometry using a FACSCalibur with CellQuest Pro software (BD Bioscience, USA). Statistical differences between groups were assessed by one-way ANOVA followed by a Duncan post-hoc test. Means labelled with different superscript letters are significantly different (p < 0.05) between organs at different sampling days.