TY - JOUR AU - Collin, Emily A. AU - Anbalagan, Srivishnupriya AU - Okda, Faten AU - Batman, Ron AU - Nelson, Eric AU - Hause, Ben M. PY - 2015 DA - 2015/03/15 TI - An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs as demonstrated by a dose-titration JO - BMC Veterinary Research SP - 62 VL - 11 IS - 1 AB - Porcine epidemic diarrhea virus (PEDV), a highly pathogenic and transmissible virus in swine, was first detected in the U.S. in May, 2013, and has caused tremendous losses to the swine industry. Due to the difficulty in isolating and growing this virus in cell culture, few vaccine studies using cell culture propagated PEDV have been performed on U.S. strains in pigs. Therefore, the objective of this study was to evaluate the humoral immune response to the selected inactivated PEDV vaccine candidate in a dose-titration manner. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-015-0357-1 DO - 10.1186/s12917-015-0357-1 ID - Collin2015 ER -