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Table 1 Geometric mean (95% CI) of virus neutralizing serum antibody titers to BVDV 1, BVDV 2, and BVDV 2 1373 from vaccinated (B, C, and D) and unvaccinated (A) calves at each time period

From: Efficacy of multivalent, modified- live virus (MLV) vaccines administered to early weaned beef calves subsequently challenged with virulent Bovine viral diarrhea virus type 2

 

Day of Study

Virus

Group

−75

−45

0

28

BVDV 1 NADL

A

157.58 (31.12 – 831.74)

60.12 (14.52 – 250.73)

15.03 (5.93 – 38.05)

35.75 (17.38 – 74.02)

B

135.29NS (28.64 – 639.14)

67.64NS (17.50 – 259.57)

107.63 * (62.68 – 183.54)

861.07 * (377.41 - 1951)

C

222.86NS (67.64 – 765.36)

101.12NS (30.27 – 337.79)

202.25 * (110.66 – 369.64)

680.28 * (225.97 - 2048)

D

194.01NS (45.56 – 903.88)

95.67NS (22.47 – 407.31)

36.25NS (12.04 – 108.38)

57.70NS (12.99 – 213.78)

BVDV 2 125c

A

107.63 (23.10 - 498)

47.83 (13.08 – 173.64)

14.22 (4.08 – 49.18)

608.87 (292.03 – 1260.69)

B

101.12NS (23.26 – 439.58)

60.12NS (15.67 – 232.32)

42.52NS (22.47 – 80.44)

809NS (455.08 – 1438.15)

C

128NS (38.85 – 418.76)

85.03NS (26.53 – 272.47)

60.12 * (26.35 – 138.14)

1820.34NS (955.42 – 3468.26)

D

128NS (40.78 – 398.93)

90.50NS (31.34 – 259.57)

29.85NS (15.24 – 58.89)

286.02NS (149.08 – 1541.37)

BVDV 2 1373

A

_

_

16.91 (5.02 – 56.44)

861.07 (424.61 – 1734.13)

B

_

_

76.10 * (47.50 – 121.09)

643.59NS (352.13 – 1176.26)

C

_

_

93.05 * (49.18 – 176.06)

1530.72NS (617.37 – 3795.30)

D

_

_

56.10NS (28.44 – 11.43)

544.95NS (245.57 – 1200.98)

  1. NS, *Means within BVDV strain and Day of Study are not significantly different (NS) from the control group A or are significantly different (*) based on Dunnett’s test at P = 0.05.