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Table 1 Effects of HPTP on renal function test (male and female rats) in acute toxicity studies

From: Protective effects of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone chalcone in indomethacin-induced gastric erosive damage in rats

Male Sodium mmol/L Potassium mmol/L Chloride mmol/L CO 2mmol/L An.gap mmol/L Urea mmol/L Creatinine μmol/L
CMC 0.5% 147.8 ± 0.5 4.9 ± 0.2 112.8 ± 0.8 15.5 ± 0.78 24 ± 0.4 8.3 ± 0.6 31.5 ± 1.6
250 mg/kg 148.5 ± 2.2 4.8 ± 0.2 109.5 ± 2.8 15.6 ± 1.3 24.8 ± 0.9 6.2 ± 0.8 29.3 ± 1.6
500 mg/kg 149.5 ± 3.2 4.9 ± 0.4 111.5 ± 2.0 14.1 ± 0.5 24.8 ± 1.0 8.2 ± 1.3 30.0 ± 0.7
1000 g/kg 151.0 ± 2.4 5.2 ± 0.3 115.8 ± 1.7 13.8 ± 0.4 27 ± 1.9 11.3 ± 1.1 35.3 ± 2.3
Female
CMC 0.5% 147.8 ± 0.6 4.9 ± 0.1 112.3 ± 1.7 13.4 ± 0.9 26.8 ± 0.5 7.2 ± 0.4 29.3 ± 1.3
250 mg/kg 147.8 ± 3.1 4.9 ± 0.1 109.3 ± 3.5 16.7 ± 1.2 27.3 ± 1.7 6.7 ± 1.1 30.0 ± 1.2
500 mg/kg 147.3 ± 1.6 5.3 ± 0.4 115.3 ± 3.7 14.3 ± 0.4 29.3 ± 1.0 7.8 ± 1.1 25.5 ± 2.0
1000 mg/kg 152.3 ± 1.7 5.4 ± 0.3 120.0 ± 2.5 14.0 ± 0.8 28.3 ± 3.0 6.6 ± 1.2 28.5 ± 2.3
  1. Values are expressed as Mean ± SEM and One-way ANOVA was used for the analysis.