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Table 2 Neosporosis in goats, lesions, diagnosis and immunolabelling in adult male goats

From: Histological and immunohistochemical characterization of the inflammatory and glial cells in the central nervous system of goat fetuses and adult male goats naturally infected with Neospora caninum

Goat Age (months) Lesions Parasite confirmation Immunolabelling
   Gliosis P. cuffs M.G.C PCR HE IHQ RCA GFAP PCNA MHC-II CD3 CD79α
1 12 +++ +++ + + - - +++ +++ + +++ + -
2 6 + + - + + + - ++ - - + -
3 12 +++ +++ + + + + +++ + ++ ++ ++ +
4 12 + ++ + + + + ++ - - ++ - -
5 6 - + - + - - - - - - + -
6 36 - + - + - - - - - + + -
7* 10 - - - - - - - - - - - -
  1. Lesions graduation: discrete (+), moderate (++) and severe (+++). Immunohistochemistry labelling graduated by the number of cells in a field of 400x: less than 10 cells per field (+), 10 to 30 cells per field (+ +), more than 30 cells per field (+ + +). *Negative Control. P. cuffs (perivascular cuffs), M.G.C (Multinucleated giant cells), HE (Hematoxilin and Eosin staining), PCR (Polimerase chain reaction), IHQ (Immunohistochemistry).