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Table 1 Neosporosis in goats, lesions, diagnosis and immunolabelling in fetuses

From: Histological and immunohistochemical characterization of the inflammatory and glial cells in the central nervous system of goat fetuses and adult male goats naturally infected with Neospora caninum

Foetus Age (days) Lesions Parasite confirmation Immunolabelling
   Gliosis P. cuffs Necrosis PCR HE IHQ RCA GFAP PCNA MHC-II CD3 CD79α
1 90 +++ +++ - + - - +++ + +++ - - -
2 90 - - - - - - - - - - - -
3 90 - - - - - - - - - - - -
4 90 +++ +++ + + + + +++ + ++ - + -
5 150 + - - + + + - ++ - - - -
6 150 + - - + + + ++ ++ - - - -
7 120 + + - + + + + - - ++ + -
8 120 ++ + + + - - ++ + - ++ - -
9* 150 - - - - - - - - - - - -
10* 90 - - - - - - - - - - - -
  1. Lesions graduation: discrete (+), moderate (++) and severe (+++). Immunohistochemistry labelling graduated by the number of cells in a field of 400x: less than 10 cells per field (+), 10 to 30 cells per field (+ +), more than 30 cells per field (+ + +). *Negative Controls. P. cuffs (perivascular cuffs), HE (Hematoxilin and Eosin staining), PCR (Polimerase chain reaction), IHQ (Immunohistochemistry).