Skip to main content
Figure 3 | BMC Veterinary Research

Figure 3

From: 6-Thioguanine and zebularine down-regulate DNMT1 and globally demethylate canine malignant lymphoid cells

Figure 3

A and B. Relative global DNA methylation with and without treatment by 6-TG or zebularine. RLGS global methylation results after treatment with 6-TG and Zeb. 6-TG and Zeb had a statistically significant (P < 0.001) reduction in relative methylation when compared to control for each cell line. All results were normalized to control values of 1 for purposes of comparison. CLGL-90 is presented in panel A and CLL 17–7 in panel B. The central bar represents the mean of the data and error bars represent the standard deviation.

Back to article page