Figure 2

DNA gel electrophoresis showing endonuclease activity in restriction landmark genomic scanning. Lanes: Lad = ladder, 1 = Control, 2 = Control + Hpa, 3 = Control + Msp, 4 = 6TG, 5 = 6TG + Hpa, 6 = Hpa + Msp, 7 = Zeb, 8 = Zeb + Hpa, 9 = Zeb + Msp. 1 kb pair DNA ladders were loaded into lane 1, followed by control, HpaII, and MspI incubated extracted DNA from the lymphoma cell line for low and high doses of 6-TG and Zeb respectively. The MSV equation $\left(\mathrm{M}\mathrm{S}\mathrm{V}=\frac{\mathrm{Densit}{\mathrm{y}}_{\mathrm{HpaII}}‐\mathrm{Densit}{\mathrm{y}}_{\mathrm{Background}}}{\mathrm{Densit}{\mathrm{y}}_{\mathrm{MspI}}‐\mathrm{Densit}{\mathrm{y}}_{\mathrm{Background}}}\right)$ was used for each treatment subset. Densities were calculated at the 2.0-2.3 kb pair region. Boxes shown in the first three lanes demonstrate the region of analysis.