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Figure 2 | BMC Veterinary Research

Figure 2

From: Insights into potential pathogenesis mechanisms associated with Campylobacter jejuni-induced abortion in ewes

Figure 2

Pathological findings in placenta of aborted ewe. (A) Placentome of an aborted ewe experimentally infected orally with ovine C. jejuni, showing severe necrotizing placentitis. Note necrotic trophoblast giant cells (arrows) exfoliated from chorionic villi. Original magnification, ×400. (B) Placentome of an aborted ewe experimentally infected with ovine C. jejuni, showing severe suppurative, necrotizing placentitis. Note a large accumulation of neutrophils and necrotic cells (asterisk) in the intervillous space. Original magnification, ×400. (C) Placentome of an aborted ewe experimentally infected with ovine C. jejuni, showing bacterial colonies (arrows) within the necrotic lesion. Original magnification, ×400. (D) Chorioallantoic membrane of an aborted ewe experimentally infected with ovine C. jejuni, showing severe necrosis of infected epithelium and containing bacterial colonies (arrows). Original magnification × 400. (E) Placenta of an aborted ewe experimentally infected with ovine C. jejuni, showing localization of majority of bacterial antigens (red-color staining) in chorioallantoic membrane. Immunohistochemistry. Fast Red. Mayer's hematoxylin counterstaining. Original magnification, ×60. (F) Chorioallantoic membrane of an aborted ewe experimentally infected with ovine C. jejuni, showing large amounts of bacterial antigens in trophoblastic epithelial cells (red-color staining) lining the epithelium. Immunohistochemistry. Fast Red. Mayer's hematoxylin counterstaining. Original magnification, ×400.

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