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Figure 3 | BMC Veterinary Research

Figure 3

From: Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament in the hindlimb of Friesian horses: review of 12 cases (2002-2012) and post-mortem analysis of the bone-ligament interface

Figure 3

Histopathology of the interface of the PSBs and the ISL. Transverse sections of a diseased and a non-diseased Friesian horse, haematoxylin and eosin staining. Note the multifocal to coalescing inflammation of the ISL which is characterized by abundant fibroblasts, lymphocytes and plasma cells in the diseased horse. The transition from ligament to bone (arrow) is very irregular in the diseased horse and compared to the non-diseased horse, there is a decrease of surface area where ligament tissue merges to bone in the diseased horse. Remaining adjacent bone shows increased osteoclastic bone resorption (osteoclasts marked with asterisks). Bone marrow was hypercellular due to invasion of lymphocytes and plasma cells.

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