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Table 4 Carprofen concentrations of synovial fluid samples Group 4 (VECHCA)

From: Preliminary study on carprofen concentration measurements after transcutaneous treatment with Vetdrop® in a microfracture joint defect model in sheep

Timepoint

5211 (VECHCA) c(ng/ml)

5212 (VECHCA) c(ng/ml)

Intra OP (day 1)

134

78

Week 1 (taken under ultrasound control)

394

229

Week 2 (taken under ultrasound control)

845

352

Week 3 (taken under ultrasound control)

461

417

Week 4 (taken under ultrasound control)

398

418

Week 5 (taken under ultrasound control)

501

288

Week 6 (taken under ultrasound control)

1350

213

Week 7 (1 week after the last application)

165

13.4