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Table 2 Carprofen concentrations of synovial fluid samples Group 3 (VECA)

From: Preliminary study on carprofen concentration measurements after transcutaneous treatment with Vetdrop® in a microfracture joint defect model in sheep

Timepoint

5203 (VECA) c(ng/ml)

5204 (VECA) c(ng/ml)

Intra OP (day 1)

25.3

13.4

Week 1 (taken under ultrasound control)

77.8

209

Week 2 (taken under ultrasound control)

293

274

Week 3 (taken under ultrasound control)

65.6

239

Week 4 (taken under ultrasound control)

195

178

Week 5 (taken under ultrasound control)

61.3

194

Week 6 (taken under ultrasound control)

327

281

Week 7 (1 week after the last application)

23.6

26.4