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Table 1 Summary of clinical signs and diagnostic data across the 3 groups of piglets from the swine bioassay

From: An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feed

 

Treatment group

(+) control group

(−) control group

Days on test

PCR

Clinical signs

PCR

Clinical signs

PCR

Clinical signs

0

Neg

Neg

Neg

Neg

Neg

Neg

1

Neg

Neg

Neg

Neg

Neg

Neg

2

Neg

Neg

19.98

Neg

Neg

Neg

3

Neg

Neg

16.32/18.84

Diarrhea

Neg

Neg

4

Neg

Neg

17.10

Diarrhea

Neg

Neg

5

Neg

Neg

16.07/15.70/16.58

V & D

Neg

Neg

6

Neg

Neg

22.13

V & D

Neg

Neg

7

Neg

Neg

21.20

Diarrhea

Neg

Neg

8

Neg

Neg

27.07

Neg

Neg

Neg

9

Neg

Neg

20.48

Neg

Neg

Neg

10

Neg

Neg

21.44

Neg

Neg

Neg

11

Neg

Neg

20.48

Neg

Neg

Neg

12

Neg

Neg

33.42

Neg

Neg

Neg

13

Neg

Neg

Neg

Neg

Neg

Neg

14

Neg

Neg

30.06

Neg

Neg

Neg

Necropsy

GI Negative

No lesions

GI positive 5/5 pigs

Lesions 5/5 pigs

GI Negative

No lesions

  1. Treatment group: Pigs fed PEDV positive/liquid antimicrobial treated feed.
  2. (+) control group: Pigs fed PEDV positive/saline treated feed.
  3. (−) control group: Pigs fed PEDV negative/saline treated feed.
  4. GI Negative: Small intestinal tracts negative by PCR & IHC.
  5. GI positive: Small intestinal tracts positive by PCR & IHC.
  6. Lesions: Histopathologic evidence of PEDV infection.
  7. DPI: Days post-ingestion of feed.
  8. V & D: vomiting & diarrhea.