TY - JOUR AU - Martins, Edivaldo AN AU - Michelacci, Yara M. AU - Baccarin, Raquel YA AU - Cogliati, Bruno AU - Silva, Luis CLC PY - 2014 DA - 2014/08/27 TI - Evaluation of chitosan-GP hydrogel biocompatibility in osteochondral defects: an experimental approach JO - BMC Veterinary Research SP - 197 VL - 10 IS - 1 AB - Articular cartilage, because of its avascular nature, has little capacity for spontaneous healing, and tissue engineering approaches, employing different biomaterials and cells, are under development. Among the investigated biomaterials are the chitosan-based hydrogels. Although thoroughly studied in other mammalian species, studies are scarce in equines. So, the aim of the present study was to investigate the biocompatibility of chitosan-GP in horse joints submitted to high mechanical loads. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-014-0197-4 DO - 10.1186/s12917-014-0197-4 ID - Martins2014 ER -