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Table 2 Normalised relative mRNA abundances of nutrient transporters and gut morphology (villus height, crypth depth, villus height:crypt depth ratio) in duodenum and jejunum of weaned pigs fed a control diet or a diet supplemented with 1% grape seed and grape marc meal extract (GSGME) or 1% spent hops (SH)

From: Effects of dietary polyphenol-rich plant products from grape or hop on pro-inflammatory gene expression in the intestine, nutrient digestibility and faecal microbiota of weaned pigs

 

Control

GSGME

SH

Relative mRNA abundance of nutrient transporters 1

Duodenum

   

SLC5A1

1.00 ± 0.30

0.81 ± 0.26

0.96 ± 0.19

SLC2A2

1.00 ± 0.29

0.93 ± 0.22

1.27 ± 0.34#

SLC2A5

1.00 ± 0.42

0.47 ± 0.34*

0.73 ± 0.27#

SLC15A1

1.00 ± 0.44

0.97 ± 0.60

1.03 ± 0.56

Jejunum

   

SLC5A1

1.00 ± 0.38

0.78 ± 0.45

0.62 ± 0.29*

SLC2A2

1.00 ± 0.49

0.67 ± 0.48#

0.54 ± 0.29*

SLC2A5

1.00 ± 0.63

0.47 ± 0.28*

0.46 ± 0.43*

SLC15A1

1.00 ± 0.51

0.53 ± 0.29*

0.69 ± 0.65

Gut morphology 2

Duodenum

   

Villus height (μm)

503 ± 29

520 ± 73

562 ± 81

Crypt depth (μm)

311 ± 51

326 ± 38

354 ± 76

Villus height:crypt depth ratio

1.65 ± 0.27

1.56 ± 0.12

1.58 ± 0.25

Jejunum

   

Villus height (μm)

471 ± 94

415 ± 33

425 ± 75

Crypt depth (μm)

277 ± 44

236 ± 42

210 ± 34*

Villus height:crypt depth ratio

1.74 ± 0.27

1.86 ± 0.29

1.98 ± 0.33

  1. SLC2A2 = solute carrier family 2 (facilitated glucose transporter) 2; SLC2A5 = solute carrier family 2 (facilitated glucose transporter) 5; SLC5A1 = sodium-glucose transporter 1; SLC15A1 = solute carrier family 15 (oligopeptide transporter), member 1. Results are shown as mean ± SD (1n = 16/group; 2n = 6/group) expressed as fold of relative mRNA abundance of the control group. *Significantly different from control (P < 0.05). #Tended to differ from control (0.05 ≤ P ≤ 0.10).