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Table 3 Definitive diagnoses* recorded for study cats

From: Hypercobalaminaemia is associated with hepatic and neoplastic disease in cats: a cross sectional study

Group Neoplasia Hepatobiliary disease Kidney disease Chronic enteropathy Other
Hypercobalaminaemia 15 8 2 3 5
(n = 33) Lymphoma (10) Neutrophilic cholangitis/ CKD (2)   Triaditis (1), FIP (1)
Duodenal adenocarcinoma (2) cholangiohepatitis (5)    Tritrichomonas (2)
Pancreatic carcinoma (1) Hepatic lipidosis (2)    Idiopathic hypercalcaemia (1)
Biliary cystadenoma (1) PVH (1)    
Metastatic plasma cell tumour (1)
Normocobalaminaemia 10 1 4 15 10
(n = 40) Lymphoma (8) Choledocholithiasis (1)    Tritrichomonas (2)
Duodenal adenocarcinoma (1)     Diabetes mellitus (1)
Neuroendocrine mass (1)     FOPS (1) FIV (1)
HES (1), HCM (1)
Gastric foreign body (1)
Pancreatitis (1)
IMPA (1)
Hypocobalaminaemia 14 0 0 13 14
(n = 41) Lymphoma (14)     EPI (5)
Pancreatitis (3)
Diabetes mellitus (2)
Acromegaly (1)
Pemphigus foliaceus (1)
Oesophageal stricture (1)
Intussusception (1)
  1. CKD: chronic kidney disease; EPI: exocrine pancreatic insufficiency; FIV: feline immunodeficiency virus; FIP: Feline infectious peritonitis; FOPS: feline oral pain syndrome; HCM: hypertrophic cardiomyopathy; HES: hypereosinophilic syndrome; IMPA: immune-mediated polyarthritis; PVH: Portal vein hypoplasia. *Definitive diagnoses were made in 33/44 (75%) hypercobalaminaemic, 40/62 (65%) normocobalaminaemic, and 41/50 (82%) hypocobalaminaemic cats. For hypercobalaminaemic cats, lymphoma types were: alimentary (gastric 3, small intestinal [including ileal], 5), extranodal (nasal, 1), epitheliotropic (1); for normocobalaminaemic cats, lymphoma types were: alimentary (gastric 1, small intestinal [including ileal] 3, colonic 1, ileocaecolic junction mass 1,), multicentric (1), epitheliotropic (1); for hypocobalaminaemic cats, lymphoma diagnoses were: alimentary (gastric 1, small intestinal [including ileal] 10), combined nasal and small intestinal (1), multicentric (1), epitheliotropic (1).