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Table 2 Expression of IHC markers by diagnosed histological type of testicular tumor

From: Canine testicular tumors: two types of seminomas can be differentiated by immunohistochemistry

Histological type of tumor Necropsy group Biopsy group
c-KIT positive tumors/% % of c-KIT positive cells PLAP positive tumors/% % of PLAP positive cells Cytokeratin positive tumors/% % of Cytokeratin positive cells CD 30 positive tumors/% % of CD 30 positive cells c-KIT positive tumors/% % of c-KIT positive cells PLAP positive tumors/% % of PLAP positive cells Cytokeratin positive tumors/% % of Cytokeratin positive cells CD 30 positive tumors/% % of CD 30 positive cells
SIMPLE TUMORS (∑) 11 39 23 <5 27 19 7 8 22 40 27 <6 33 43 8 23
MIXED TUMORS (∑) 33 23 25 <5 66 25 8 5 44 26 22 <7 44 46 11 30
LCT simple 5 5 21 <5 15 16 5 10 0 0 16 <5 20 60 6 30
with SCT 20 20 40 <5 60 23 20 5 0 0 0 0 100 50 0 0
with IT SEM 33 10 0 0 60 17 0 0 100 20 100 10 100 5 0 0
with DIF SEM 50 60 0 0 40 40 0 0 75 28 0 0 0 0 0  
SCT simple 0 0 28 <5 71 32 14 10 6 5 31 <5 62 51 12 27
with LCT 20 20 40 <5 60 23 20 5 0 0 0 0 100 50 0 0
with DIF SEM 50 5 50 5 100 30 0 0 0 0 25 5 50 65 25 30
IT SEM simple 14 5 14 5 28 5 0 0 0 0 33 10 33 5 0 0
with LCT 33 10 0 0 60 17 0 0 100 20 100 10 100 5 0 0
DIF SEM simple 50 90 25 5 25 5 25 5 45 43 15 11 10 12 0 0
with SCT 50 5 50 5 100 30 0 0 0 0 25 5 50 65 25 30
with LCT 50 60 0 0 40 40 0 0 75 28 0 0 0 0 0  
PNST 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
TERAT 0 0 0 0 0 0 0 0 0 20 0 <5 100 50 100 10
IGCNU 16   33 <5 16 5 0 0 0 0 100 5 0 0 0 0
MET. T. LYMPH 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Total 16 32 23 <5 35 21 7 7 26 36 26 <6 29 44 8 25
  1. Note: ∑, sum; DIF SEM, diffuse seminoma; IGCNU, intratubular germ cell neoplasia of undifferentiated origin; IT SEM, intratubular seminoma; LCT, Leydig cell tumors; MET. T. LYMPH, metastatic tumor – lymphoma; PLAP, placental alkaline phosphatase; PNST, peripheral nerve sheat tumor; SCT, Sertoli cell tumor; TERAT, teratoma.