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Table 1 Immunization, mortality, and gross lesions in the internal organs of chickens after challenge in experiment 1

From: Oral immunization with an attenuated Salmonella Gallinarum mutant as a fowl typhoid vaccine with a live adjuvant strain secreting the B subunit of Escherichia coliheat-labile enterotoxin

Group Immunizationa n Mortality (%) Gross lesionb
Liver Spleen
Prime Booster ENc NFd EN NF
A JOL916/JOL1229 JOL916/JOL1229 10 10* 0.7±1.1* 0.4±1.0* 0.4±1.0* 0.7±0.9*
B JOL916/JOL1229 JOL916 10 10* 0.6±1.0* 0.8±1.1* 0.7±1.2* 0.5±1.0**
C PBS PBS 10 70 2.1±1.4 2.1±1.4 2.1±1.4 2.3±1.3
  1. a JOL916 is a vaccine strain and JOL1229 is an LTB protein-secreting strain for adjuvant. JOL916/JOL1229 is a mixture consisting of 4 parts JOL916 and 1 part JOL1229. The dose of immunization was 1 × 108 CFU in a volume of 200 μl.
  2. b Gross lesion score (mean ± SEM).
  3. c Enlargement.
  4. d Necrotic foci.
  5. Asterisks indicate a significant difference compared to the control group (*p < 0.05, **p < 0.01). n, numbers of the chickens used.