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Table 3 MMP-9, MMP-2, MT1-MMP, TIMP-1, TIMP-2, VEGF-A, VEGF-164 and RECK mRNA expression in high grade and low grade T-cell lymphomas and HG B-cell lymphomas

From: The role of vascular endothelial growth factor and matrix metalloproteinases in canine lymphoma: in vivo and in vitro study

Genes T-cell lymphoma B-cell lymphoma
tt High grade Low grade High grade
MMP-2 0.18 ± 0.22 0.17 ± 0.20 0.26 ± 0.29
MMP-9 0.82 ± 0.15 a 0.12 ± 0.28 0.01 ± 0.03
MT1-MMP 1.01 ± 1.08 a 0.81 ± 0.86 0.10 ± 0.11
TIMP-1 1.07 ± 1.98 a 0.63 ± 0.92 0.13 ± 0.21
TIMP-2 0.15 ± 0.28 0.16 ± 0.32 0.14 ± 0.19
RECK 0.93 ± 1.26 a 1.67 ± 2.76 0.06 ± 0.12
VEGF-A 1.21 ± 1.65 0.35 ± 0.43 0.67 ± 0.99
VEGF-164 1.11 ± 0.92 0.39 ± 0.88 0.49 ± 0.65
  1. Data are expressed as relative quantification values (arbitrary units, mean ± SD)
  2. aSignificant difference between high grade T-cell and B-cell lymphomas (Mann–Whitney test; p < 0.05).