Variable | Robenacoxib | Meloxicam | Total | P value* |
---|---|---|---|---|
Number of dogs | 118 | 56 | 174 | |
Age (years) | 5.9 (3.9) | 5.2 (4.1) | 5.7 (3.9) | 0.20 |
Body weight (kg) | 20.8 (12.3) | 19.0 (11.1) | 20.2 (11.9) | 0.42 |
Sex and neutered status | ||||
Male not neutered | 14 (11.9%) | 8 (14.3%) | 22 (12.6%) | 0.37 |
Female not neutered | 87 (73.7%) | 40 (71.4%) | 127 (73.0%) | |
Male neutered | 5 (4.2%) | 0 (0%) | 5 (2.9%) | |
Female neutered | 12 (10.2%) | 8 (14.3%) | 20 (11.5%) | |
Pre-surgery pain (VAS) | ||||
▪ At rest | 2.0 (5.4) | 1.7 (2.3) | 1.9 (4.6) | 0.21 |
▪ At palpation/manipulation | 5.2 (10.2) | 4.2 (6.3) | 4.9 (9.2) | 0.64 |
Type of surgery** | ||||
▪ Ovariectomy | 37 (31%) | 22 (39%) | 59 (34%) | 0.31 |
▪ Ovario-hysterectomy | 28 (24%) | 10 (18%) | 38 (22%) | 0.44 |
▪ Mammary chain excision | 30 (25%) | 15 (27%) | 45 (26%) | 0.85 |
▪ Gastro-intestinal surgery | 5 (4%) | 0 (0%) | 5 (3%) | 0.18 |
▪ Genito-urinary surgery | 5 (4%) | 2 (4%) | 7 (4%) | 1.0 |
▪ Thoracic surgery | 1 (1%) | 0 (0%) | 1 (1%) | 1.0 |
▪ Other soft tissue surgery | 22 (19%) | 10 (18%) | 32 (18%) | 1.0 |
Duration of surgery (hours) | 0.85 (0.52) | 0.68 (0.35) | 0.79 (0.48) | 0.037 |
Duration of intubation (hours) | 1.4 (0.77) | 1.2 (0.60) | 1.3 (0.73) | 0.20 |
Time between injection of robenacoxib or meloxicam and extubation (hours) | 1.6 (0.81) | 1.4 (0.63) | 1.5 (0.76) | 0.18 |
Duration of oral dosing (days) | 11.3 (22.2) | 10.9 (3.0) | - | 0.92 |