GR binding and (hydroxyl)methylation status of the promoter of nuclear-encoded mitochondrial genes. Values are mean ± SEM, n = 6/breed. * means p < 0.05 between breeds, ** means p < 0.01. GREs, glucocorticoid response elements. (A) Schematic structure of IDH2 promoter. (B) GR binding to IDH2 promoter. (C) DNA methylation and hydroxymethylation status of the CpG island on IDH2 promoter. (D) Schematic structure of AK1 promoter. (E) GR binding to AK1 promoter. (F) DNA methylation and hydroxymethylation status of the CpG island on AK1 promoter. (G) Schematic structure of ATP5H promoter. (H) GR binding to ATP5H promoter. (I) DNA methylation and hydroxymethylation status of ATP5H promoter.