Table 3 PrP Sc epitope mapping immunolabeling results of hemal nodes and retropharyngeal lymph nodes from naturally and experimentally scrapie-infected sheep
From: Accumulation profiles of PrPScin hemal nodes of naturally and experimentally scrapie-infected sheep
Animal ID | Age (months) | Source of scrapie | Clinical status | Prnp | Anti-prion mAbs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
12B2 | P4 | 1E4 | 8G8 | L42 | SAF84 | F99/97.6.1 | |||||
(Hemal nodes/Lymph nodes) | |||||||||||
3339 | 37 | Natural | Preclinical | ARQ/ARQ | / | / | / | / | / | / | / |
4071 | 29 | Natural | Preclinical | ARQ/ARQ | / | / | / | / | / | / | / |
3403 | 37 | Natural | Clinical | ARQ/ARQ | / | / | n | / | / | / | / |
3727 | NA | Natural | Clinical | ARQ/ARQ | / | / | / | n | / | / | / |
3768 | 30 | Natural | Clinical | ARQ/ARQ | / | / | / | / | / | / | / |
4063 | 29 | Natural | Clinical | ARQ/VRQ | / | / | / | / | / | / | / |
2933 | 46 | Natural | Clinical | ARQ/VRQ | / | / | / | / | / | / | / |
3588 | 30 | Natural | Clinical | ARQ/VRQ | / | / | / | / | / | / | / |
3753 | 35 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3755 | 12 | Natural | Clinical | VRQ/VRQ | / | / | n | / | / | / | / |
3774 | 48 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3776 | 50 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3777 | 50 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3806 | 28 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3807 | 25 | Natural | Clinical | VRQ/VRQ | / | / | / | / | / | / | / |
3823 | 13 | Exp- BC | Preclinical | ARQ/ARQ | / | / | / | / | / | / | / |
3820 | 24 | Exp- PRP | Preclinical | ARQ/ARQ | n | / | n | / | / | / | / |
3628 | 12 | Exp- WB | Preclinical | ARQ/VRQ | / | / | / | / | / | / | / |
4132 | 13 | Exp- WB | Preclinical | ARQ/VRQ | / | / | / | / | / | / | / |
4118 | 13 | Exp- PBMC | Preclinical | ARQ/VRQ | / | / | / | / | / | / | / |
4494 | 16 | Exp- PBMC | Preclinical | VRQ/VRQ | / | / | / | / | / | / | / |
4381 | 11 | Exp- B cells* | Preclinical | VRQ/VRQ | / | / | / | / | / | / | / |
4382 | 11 | Exp- B cells* | Preclinical | VRQ/VRQ | / | / | n | / | / | / | / |
4385 | 11 | Exp- B cells | Preclinical | VRQ/VRQ | / | / | / | / | / | / | / |
4489 | 16 | Exp- B cells | Preclinical | VRQ/VRQ | / | / | / | / | / | / | / |