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Table 2 Proportion of scrapie-infected sheep 1 in which PrP Sc was detected in abdominal hemal nodes

From: Accumulation profiles of PrPScin hemal nodes of naturally and experimentally scrapie-infected sheep

Prnp

Total sheep

Proportion sheep with PrPScdetected in hemal nodes

Row percentage

Natural exposure

Experimental exposure

Preclinical

Clinical

Preclinical2

Clinical

ARQ/ARQ

30

13/14

8/8

3/6

2/2

87%

ARQ/VRQ

24

3/4

3/4

13/16

0

79%

VRQ/VRQ

28

3/3

8/8

11/17

0

79%

Column percentage

 

90%

95%

69%

100%

82%

  1. 1PrPSc detected by IHC in both the retropharyngeal and a mesenteric lymph node of all sheep.
  2. 2The preclinical time-point for the experimental exposure of VRQ/VRQ group was at 4-10 months after transfusion of weaned lambs.