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Table 2 Over-represented cellular pathways in canine mammary cancer

From: Gene expression profiles in canine mammary carcinomas of various grades of malignancy

Cellular pathway 1vs 2 1vs 3 2vs 3
5HT1 type receptor mediated signaling pathway X X  
Acetate utilization   X X
Alzheimer disease-amyloid secretase pathway   X  
Angiogenesis   X X
Apoptosis signaling pathway X X X
Axon guidance mediated by semaphorins   X X
Beta1 adrenergic receptor signaling pathway X X  
Beta2 adrenergic receptor signaling pathway X X  
Cadherin signaling pathway   X X
Cytoskeletal regulation by Rho GTPase   X X
DNA replication   X X
Endothelin signaling pathway   X X
GABA-B_receptor_II_signaling X X  
Glycolysis X X X
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway X X X
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway X X  
Histamine H2 receptor mediated signaling pathway X X  
Huntington disease   X X
Inflammation mediated by chemokine and cytokine signaling pathway X X X
Interleukin signaling pathway   X X
Metabotropic glutamate receptor group II pathway X X  
Metabotropic glutamate receptor group III pathway X X  
Muscarinic acetylcholine receptor 2 and 4 signaling pathway X X  
P53 pathway feedback loops 1 X X  
PDGF signaling pathway X X  
PI3 kinase pathway X X X
Pentose phosphate pathway X X  
Ras Pathway X X  
Transcription regulation by bZIP transcription factor   X X
VEGF signaling pathway   X X
Wnt signaling pathway X X X
p53 pathway feedback loops 2   X X
p53 pathway   X X
  1. Cellular pathways in which are involved significantly up-regulated genes in the examined tumour groups. The analysis was conducted using PANTHER Database (http://www.pantherdb.org). The pathway activity in the tumour group 1 vs 2, 1 vs 3 and 2 vs 3 is marked as X.