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Table 3 CMT-associated ESR1 haplotypes in the ESS cases and controls

From: The ESR1 gene is associated with risk for canine mammary tumours

Haplotype Frequency P Raw a P Bonf b P Perm c OR
  Total Cases Controls     
ESR1 EX 2 and ESR1 EX 4 (rs21960513 and ss244244343)
TA 0.668 0.701 0.610 0.035 0.381 0.549 1.5
CA 0.318 0.293 0.363 0.098 1.000 0.941 0.7
CG 0.014 0.006 0.027 0.052 0.572 0.741 0.2
ESR1 INT 7-8a, –b and ESR1 EX 8 (ss244244344, ss244244345 and ss244244346)
GTG 0.791 0.818 0.744 0.047 0.517 0.683 1.5
ACA 0.091 0.070 0.129 0.024 0.264 0.480 0.5
  1. aP-value from chi-square test in Haploview.
  2. b Corrected for the number of LD blocks available (11).
  3. c Permutation P-value from Haploview, 10,000 permutations.
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