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Table 2 CMT-associated ESR1 SNPs in the ESS cases and controls

From: The ESR1 gene is associated with risk for canine mammary tumours

SNP

NCBI SNP ID

Minor allele

Frequency of minor allele

Major allele

P Raw a

P Bonf b

P Perm c

OR

   

Cases

Controls

     

ESR1 INT 7-8a

ss244244344

A

0.033

0.106

G

0.002

0.021

0.018

0.3

ESR1 EX 2

rs21960513

C

0.299

0.391

T

0.033

0.362

0.042

0.7

ESR1 EX 4

ss244244343

G

0.006

0.027

A

0.052

0.568

0.155

0.2

  1. (n = 165 and n = 94, respectively, after QC).
  2. aP-value from chi-square test in PLINK.
  3. b Bonferroni corrected for the number of LD blocks (11).
  4. c EMP1 value after 10,000 permutations in PLINK.
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BMC Veterinary Research

ISSN: 1746-6148

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