Efficacy and toxicity of thirteen plant leaf acetone extracts used in ethnoveterinary medicine in South Africa on egg hatching and larval development of Haemonchus contortus

Table 2 EC ₅₀ for Egg Hatch assay (EHA) and Larval Development test (LDT) with their corresponding cytotoxicity values and selectivity index (SI) for thirteen plant species

Names of plants	EHA EC₅₀ ± SE	LDT EC₅₀ ± SE	LC₅₀	SI EHA	SI LDT
*Apodytes dimidiata*	5.70 ± 0.23	4.13 ± 0.56	0.00396	0.000695	0.00096
*Brachylaena discolor*	3.55 ± 0.27	17.23 ± 5.47	0.00752	0.00212	0.00044
*Clausena anisata*	1.80 ± 0.09	2.07 ± 0.15	0.17186	0.09548	0.08302
*Clerodendrum glabrum*	1.48 ± 0.07	12.97 ± 2.33	0.04251	0.02872	0.00328
*Cyathea dregei*	17.64 ± 4.65	17.93 ± 6.66	0.00332	0.00019	0.00019
*Heteromorpha trifoliata*	0.62 ± 0.02	0.64 ± 0.10	0.04252	0.06858	0.06644
*Indigofera frutescens*	7.11 ± 1.10	7.58 ± 1.05	0.1044	0.01468	0.01377
*Leucosidea sericea*	1.08 ± 0.11	1.27 ± 0.07	0.0515	0.04769	0.04055
*Maesa lanceolata*	0.72 ± 0.05	1.68 ± 0.10	0.01577	0.0219	0.00939
*Melia azedarach*	6.24 ± 0.20	10.96 ± 1.79	0.14466	0.02318	0.0137
*Milletia grandis*	5.57 ± 0.33	6.11 ± 1.04	0.05336	0.00958	0.00873
*Strychnos mitis*	16.56 ± 4.88	16.94 ± 4.71	0.01721	0.00104	0.00102
*Zanthoxylum capense*	13.26 ± 0.24	13.64 ± 3.44	0.02095	0.00643	0.00153

Note: all values for EHA, LDT and LC₅₀ in mg/ml; Albendazole was positive control and recorded 100% inhibition at all concentrations (0.008 to 25 μg/ml) used, while 2.5% DMSO recorded < 10% inhibition.

ISSN: 1746-6148