Rabies viral antigen and RNA pattern comparison between paralytic and furious rabies. Rabies antigen parameters (A-C) and RNA levels (D) are shown for all CNS regions examined. Blue and red bars refer to paralytic and furious rabies, respectively. S = sacral cord, L = lumbar cord, T = thoracic cord, C = cervical cord, M = medulla oblongata, P = pons, Mb = midbrain, Cb = cerebellum, Th = thalamus, Cd = caudate nucleus, H = hippocampus, O = occipital lobe, Tm = temporal lobe, Pr = parietal lobe, and F = frontal lobe. The viral RNA is expressed as the copy number of rabies/µg total RNA × 108. Asterisks indicate significantly greater RABV antigen or RNA burden in the furious subtype compared to the paralytic subtype.