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Table 4 Mean plasma half-life and other descriptive statistics of cimicoxib in 4 dogs breeds after a single oral administration of cimicoxib at 2 mg/kg

From: Pharmacokinetic/pharmacodynamic modeling for the determination of a cimicoxib dosing regimen in the dog

  Anglo-French hounds Pointers Cavalier King Charles spaniels Bernese mountain dogs
Number of dogs 10 10 10 10
Minimum (h) 2.0 2.5 1.9 3.2
Maximum (h) 4.0 5.9 3.5 5.8
Mean (h) 3.2a,b 3.9a,c 2.7b 4.4c
Standard Deviation (h) 0.7 1 0.6 0.9
CV (%) 22.7 26.5 21.6 20.1
  1. a,b,c : The values indexed by the same letter are not significantly different.