Figure 2

Individual plasma concentrations of cimicoxib (ng/mL) vs. time (h) after a single intravenous administration of cimicoxib (2 mg/kg) in 12 beagle dogs. Visual inspection of the figure confirms what has been observed in Figure 1 with the existence of the same 2 subgroups of dogs named “Poor Metabolizers” (red dotted line) and “Extensive Metabolizers” (blue continuous line). Letters indicates names of dogs.