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Table 5 Odds ratios and p-values for the mixed logistic regression model describing the effect of body system treated, number of antimicrobials used and the use of neomycin upon treatment failure in 676 OSVS records, when antimicrobials were used in treatment (July 1, 2007 – July 30, 2009)

From: Describing antimicrobial use and reported treatment efficacy in Ontario swine using the Ontario swine veterinary-based Surveillance program

Fixed effects

Odds ratio

Standard error

P-value

System

  

0.01

GI

Referent

-

-

Multisystemic

3.14

0.99

<0.01

Musculoskeletal

2.39

1.00

0.04

Other

1.96

0.76

0.08

Respiratory

2.40

0.75

<0.01

Not recorded

1.47

0.78

0.46

Number of antimicrobials used

  

0.01a

1

Referent

-

-

2

2.29

0.72

<0.01

3 or more

7.56

6.10

0.01

Neomycin

0.34

0.15

0.02

Intercept

1.02

0.41

0.97

Random intercepts

Variance

Standard error

P-value

Practitioner

0.81

0.62

<0.01b

Farm

0.60

0.39

 
  1. aP-value for the likelihood ratio test comparing the model with and without the system variable.
  2. bP-value for the likelihood ratio test comparing the random effects model to the fixed-effects model alone.