Figure 1
From: A fully caninised anti-NGF monoclonal antibody for pain relief in dogs
NGF and anti-NGF antibody sequences. A) Alignment of the mature peptide sequence of NGF from human, mouse & dog. Identical amino acids are indicated by dots and similar amino acids are underlined. B) Variable heavy &C) variable light chain sequences of the anti-NGF antibody αD11 aligned to the caninised antibody NV-01. Identical amino acids are indicated by dots and similar amino acids are underlined. Complementarity-determining regions (CDR) are boxed.