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Table 4 Telemetric cystometry: evolution of detrusor pressure and voided volume during the different drug administrations

From: Urodynamic investigation by telemetry in Beagle dogs: validation and effects of oral administration of current urological drugs: a pilot study

Drugs

Pdet th (mm Hg)

Vv (mL)

 

Day 0

Day 1

Day 8

Day 15

Day 0

Day 1

Day 8

Day 15

Phenylpropanolamine

31.9 ± 8.5

28.4 ± 8.2

28.2 ± 8.5

24.5 ± 9.1

101.4 ± 46.2

109.9 ± 43.2

112.2 ± 46.1

175.1 ± 50.1

Oestriol

22.4 ± 6.9

25.7 ± 6.9

26.1 ± 7.2

26.1 ± 7.1

139.2 ± 36.4

160.6 ± 35.9

141.19 ± 39.6

121.3 ± 38.3

Oxybutynin

26.6 ± 7.5

30.1 ± 6.3

25.7 ± 7.5

26.1 ± 7.3

64.9 ± 40.3

79.6 ± 31.8

55.9 ± 41.5

71.4 ± 40.2

Bethanechol

26.9 ± 7.9

34.7 ± 7.6

21.91 ± 7.5

24.6 ± 6.7

84.2 ± 45.4

85.8 ± 42.8

83.9 ± 43.1

129.5 ± 40.9

Duloxetine

30.3 ± 7.1

30.4 ± 7.9

30.1 ± 8.3

34.7 ± 7.9

119.5 ± 39.1

186.6 ± 45.6

141.7 ± 49.5

174.8 ± 45.7

  1. Pdet th = Detrusor threshold pressure (mmHg); Vv = Bladder voided volume (mL).
  2. Data are expressed as LSMean ± SEM.