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Table 3 Transcript levels of genes encoding fiber-specific MHC isoforms and regulators of muscle fiber distribution in LD muscle of pigs fed either a control diet or a diet supplemented with 750 mg niacin/kg diet for 3 wk

From: Niacin supplementation increases the number of oxidative type I fibers in skeletal muscle of growing pigs

 

Control

Niacin

Pvalue

n = 12

n = 13

(ANOVA)

 

Relative mRNA level (fold of control)

 

Fiber-specific MHC isoforms

MYH7 (type I-specific)

1.00 ± 0.29

1.26 ± 0.42

0.139

MYH2 (type IIA-specific)

1.00 ± 0.40

0.65 ± 0.21

0.023

MYH4 (type IIB-specific)

1.00 ± 0.51

0.67 ± 0.27

0.086

Regulators of fiber distribution

PGC-1α

1.00 ± 0.91

1.49 ± 0.98

0.309

PGC-1β

1.00 ± 0.24

1.33 ± 0.31

0.021

  1. Values are means ± SD.