Table 6 Clinical signs reported and number of dogs affected per treatment group
Clinical sign* | Cyclosporine A1(n = 25) | Cyclosporine A and prednisolone1(n = 23) | p-value |
|---|---|---|---|
Digestive tract disorders | 20 (14) | 12 (8) | 0.1810 |
Abdominal pain | 1 | 0 | 0.3589 |
Digestive tract hypermotility | 0 | 1 | 0.3169 |
Flatulence | 1 | 1 | 0.9762 |
Diarrhea | 5 (5) | 7 (6) | 0.5815 |
Stomatitis | 0 | 1 | 0.3169 |
Vomiting | 13 (10) | 2 (2) | 0.0116 |
Renal and urinary disorders | 4 (3) | 7 (5) | 0.3726 |
Cystitis | 0 | 2 (2) | 0.1441 |
Polyuria | 1 | 2 (2) | 0.5223 |
Uremia | 0 | 1 | 0.3169 |
Urinary incontinence | 1 | 0 | 0.3589 |
Urine abnormalities | 2 (2) | 2 (2) | 0.9485 |
Skin and appendages disorders | 10 (8) | 3 (3) | 0.1080 |
Bacterial skin infection | 1 | 1 | 0.9762 |
Dermatitis | 0 | 1 | 0.3169 |
Erosion | 0 | 1 | 0.3169 |
Fungal skin infection | 1 | 0 | 0.3589 |
Papilloma | 1 | 0 | 0.3589 |
Pruritus | 1 | 0 | 0.3589 |
Pyoderma | 6 | 0 | 0.0264 |
Systemic disorders | 2 (2) | 13 (8) | 0.0190 |
Abnormal test result | 1 | 3 (3) | 0.2717 |
Anorexia | 0 | 1 | 0.3169 |
Lethargy | 0 | 4 (4) | 0.0329 |
Polydipsia | 1 | 4 (4) | 0.1384 |
Pyrexia | 0 | 1 | 0.3169 |
Others | |||
Hyperactivity | 1 | 0 | 0.3589 |
Tachypnea | 1 | 1 | 0.9762 |
Musculoskeletal disorder | 1 | 0 | 0.3589 |
Acid–base disorder | 0 | 1 | 0.3169 |
Conjunctivitis | 2 (2) | 1 | 0.6226 |
Otitis externa | 2 (2) | 0 | 0.1798 |